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ProDOL revolutionizes protein quantification in living cells

Thursday 8 August 2024 1815

WEB Our method named Calmet enables quantitative determination of the concentration of

We report the use of NMR-detected hydrogendeuterium exchange of quenched cell lysates to measure the concentration of proteins in living cells. Our method named Calmet enables quantitative determination of the concentration of proteins in living cells. Thereby ProDOL can be used to rapidly and robustly determine optimal labelling conditions for protein-tag labelling and. We report the use of NMR-detected hydrogendeuterium exchange of quenched cell lysates to measure. Thereby ProDOL can be used to rapidly and robustly determine optimal labelling conditions for protein-tag labelling and.